A recent large study in JAMA showed amoxicillin is as effective as augmentin for treating sinusitis.  This tallies with our national antibiotic guideline advice.  It is important to recognise that sinusitis does not usually require antibiotic therapy.  

Check out the paper mentioned

Savage TJ, Butler AM, Kronman MP, Durkin MJ, Sreedhara SK, Kabbani S, Hicks LA, Huybrechts KF. Amoxicillin-Clavulanate vs Amoxicillin for Acute Sinusitis in Adults. JAMA. 2026 May 19;335(19):1694-1705. doi: 10.1001/jama.2025.26902. PMID: 41999289; PMCID: PMC13092118.

Check out the national antibiotic guidelines – Te Whata Kura

Check out the RNZCUC Research Network

Check out the Bootcamp conference, incorporating the research network meeting

Check out the Research Review

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This podcast is intended to assist in ongoing medical education and peer discussion for qualified health professionals.  Please ensure you work within your scope of practice at all times.  For personal medical advice, always consult your usual doctor